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"funnel factor"

português translation: molécula ou fator gargalo

18:42 Sep 28, 2020
Traduções de inglês para português [ PRO]
Medical - Medicina: Assistência médica / Cancer
inglês termo ou frase: "funnel factor"
Is a molecule where several oncogenic signals converge and drive the proliferative signal downstream. This transformation-inducing signal inexorably passes and is canalized through the funnel factor. Funnel factors provide a clear reflection of the tumor’s transforming potential regardless of the triggering genetic alteration upstream. The level of expression of these factors should correlate with the degree of malignancy of the tumor and the most relevant clinical parameters, such as metastasis and survival. Therefore, they may reflect the molecular information and transformation potential for each tumor.
Wendy Gosselin
Argentina
Local time: 10:52
português tradução:molécula ou fator gargalo
Explicação:
Sugestão meio visual, já que pela descrição é uma molécula que atua como gargalo por onde passam vários sinalizadores oncogênicos à montante, sendo que depois de passar pelo "gargalo", tais sinais proliferativos são dirigidos para baixo na via e acabam piorando o prognóstico do tumor

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Note added at 23 hrs (2020-09-29 17:56:05 GMT)
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Kind of a visual suggestion, it seems these molecules act as a "bottleneck" that converge upstream oncogenic signals and drive the proliferative signal downstream.
Resposta selecionada de:

Silvia Tratnik
Local time: 10:52
Grading comment
Silvia, it seems like this term has no existing translation but your proposal seems fantastic!
4 pontos KudoZ serão concedidos para esta resposta



Resumo de todas as traduções sugeridas
3Fator de Afunilamento
Nathalia Grohs
3fator de concentração
Clauwolf
3molécula ou fator gargalo
Silvia Tratnik
3fator de convergência
Alessandro Nogueira


  

Respostas


4 horas   confiança: Answerer confidence 3/5Answerer confidence 3/5
Fator de Afunilamento


Explicação:
I think the word afunilamento will be closer with the original meaning. I know its used n the field, but don't seams like it have a direct translation to Portuguese.

Nathalia Grohs
Brasil
Local time: 10:52
Falante da língua materna: português
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1 hora   confiança: Answerer confidence 3/5Answerer confidence 3/5
fator de concentração


Explicação:
:)

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Note added at 16 hrs (2020-09-29 11:39:06 GMT)
--------------------------------------------------

Now I read again your context and it refers to a molecule or substance (molecule is a symbol), and not cold numbers:)

Clauwolf
Local time: 10:52
Trabalha no campo
Falante da língua materna: português
Pontos PRO na categoria: 126
Notas para o respondente
Consulente: Oi Clauwolf! I'm not sure this is the same thing and here's why: when I Google "funnel factor," it never appears as a number (more as a molecule identified as a funnel factor) but fator de concentração appears to be a measurement, i.e., "e um fator de concentração de 22." Any thoughts?

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23 horas   confiança: Answerer confidence 3/5Answerer confidence 3/5
molécula ou fator gargalo


Explicação:
Sugestão meio visual, já que pela descrição é uma molécula que atua como gargalo por onde passam vários sinalizadores oncogênicos à montante, sendo que depois de passar pelo "gargalo", tais sinais proliferativos são dirigidos para baixo na via e acabam piorando o prognóstico do tumor

--------------------------------------------------
Note added at 23 hrs (2020-09-29 17:56:05 GMT)
--------------------------------------------------

Kind of a visual suggestion, it seems these molecules act as a "bottleneck" that converge upstream oncogenic signals and drive the proliferative signal downstream.

Silvia Tratnik
Local time: 10:52
Especialista no campo
Falante da língua materna: português
Pontos PRO na categoria: 12
Grading comment
Silvia, it seems like this term has no existing translation but your proposal seems fantastic!
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2 dias 6 horas   confiança: Answerer confidence 3/5Answerer confidence 3/5
fator de convergência


Explicação:
Here is an example of the term "fator de convergência" in this context.

https://www.docsity.com/pt/modelagem-molecular-aplicada-a-so...

Exemplo de sentença(s):
  • "Se a mesma for menor que um fator de convergência ΔV estipulado, o processo é interrompido."
Alessandro Nogueira
Brasil
Local time: 10:52
Especialista no campo
Falante da língua materna: português
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