Glossary entry (derived from question below)
English term or phrase:
q.d vs. o.d (=every day vs. once daily)
English answer:
the daily dose taken once daily vs the total daily dose (possibly spread over the whole day)
Added to glossary by
Andrew Tishin
Jul 30, 2022 22:27
1 yr ago
102 viewers *
English term
q.d vs. o.d (=every day vs. once daily)
English
Medical
Medical: Health Care
Dear colleagues, could you kindly help me understand the reason for distinguishing these two terms in this context?
(https://uroweb.org/guidelines/urological-infections/chapter/...
Table 3: Suggested regimens for empirical parenteral antimicrobial therapy in uncomplicated pyelonephritis
Second-line treatment
Cefepime 1-2 g b.i.d
Piperacillin/tazobactam 2.5-4.5 g t.i.d
Gentamicin 5 mg/kg *q.d*
Amikacin 15 mg/kg *q.d*
Last-line alternatives
Imipenem/cilastatin 0.5 g t.i.d
...
Plazomicin 15 mg/kg *o.d*
Notes:
b.i.d = twice daily; t.i.d = three times daily; q.d = every day; o.d = once daily.
(https://uroweb.org/guidelines/urological-infections/chapter/...
Table 3: Suggested regimens for empirical parenteral antimicrobial therapy in uncomplicated pyelonephritis
Second-line treatment
Cefepime 1-2 g b.i.d
Piperacillin/tazobactam 2.5-4.5 g t.i.d
Gentamicin 5 mg/kg *q.d*
Amikacin 15 mg/kg *q.d*
Last-line alternatives
Imipenem/cilastatin 0.5 g t.i.d
...
Plazomicin 15 mg/kg *o.d*
Notes:
b.i.d = twice daily; t.i.d = three times daily; q.d = every day; o.d = once daily.
Responses
+2
1 day 15 hrs
English term (edited):
q.d. quaque die "once a day" vs. o.d. omni die "daily dose"
Selected
the daily dose taken once daily vs the total daily dose (possibly spread over the whole day)
in practical terms, how it's used: OFTEN quasi-synonyms - the medicine is to be taken every day, in one daily dose.
BUT there IS a difference in meaning
q.d. = quaque die "once a day" / "once every day" that daily dose has to be taken as once / in one dosing.
o.d. = omni die "every day" as in "that much for the whole day", usually but not necessarily - in one dosing.
that could be meaningful difference if the medication is administered continuously (like "i.v." intravenal route) - as administering the daily dose of medicine through a slow continuous drip is hardly taking the daily dose "once a day" - like when taking pills "once a day".
FROM
British National Formulary (BNF)
Key information on the selection, prescribing, dispensing and administration of medicines:
Latin abbreviations
Directions should be in English without abbreviation. However, Latin abbreviations have been used when prescribing.
The following is a list of appropriate abbreviations. It should be noted that the English version is not always an exact translation.
a. c. = ante cibum (before food)
b. d. = bis die (twice daily)
o. d. = omni die (every day)
o. m. = omni mane (every morning)
o. n. = omni nocte (every night)
p. c. = post cibum (after food)
p. r. n. = pro re nata (when required)
q. d. s. = quater die sumendum (to be taken four times daily)
q. q. h. = quarta quaque hora (every four hours)
stat = immediately
t. d. s. = ter die sumendum (to be taken three times daily)
t.i.d. = ter in die (three times daily)
https://bnf.nice.org.uk/about/abbreviations-and-symbols/
Medical Definition of Quaque die (on prescription)
Medical Editor: Charles Patrick Davis, MD, PhD
Reviewed on 3/29/2021
Quaque die (on prescription): Seen on a prescription, qd (or, written with periods, q.d.) means one a day (from the Latin quaque die). The abbreviation is sometimes written without a period in capital letters as "QD". However it is written, it is one of a number of hallowed abbreviations of Latin terms that have been traditionally used in prescriptions to specify the frequency with which medicines should be taken.
Other examples include:
-- b.i.d. (bid or BID) is twice a day; b.i.d.. stands for "bis in die" (which means, in Latin, twice a day).
-- t.i.d. (or tid or TID) is three times a day ; t.i.d. stands for "ter in die" (in Latin, 3 times a day).
-- q.i.d. (or qid or QID) is four times a day; q.i.d. stands for "quater in die" (in Latin, 4 times a day).
-- q_h: If a medicine is to be taken every so-many hours, it is written "q_h"; the "q" standing for "quaque" and the "h" indicating the number of hours. So, for example, "2 caps q4h" means "Take 2 capsules every 4 hours."
https://www.medicinenet.com/quaque_die_on_prescription/defin...
ALSO
q.d. every day (from Latin quaque die)
vs
o.d. every day, usually regarded as once daily (from Latin omni die). Generally written in lowercase.
https://en.wikipedia.org/wiki/List_of_medical_abbreviations:...
https://en.wikipedia.org/wiki/List_of_medical_abbreviations:...
Peer comment(s):
agree |
Clauwolf
: right, and cp (consult your physician):)
1 hr
|
Thanks!
|
|
agree |
Yvonne Gallagher
: Still be good to get a medical opinion. //You seem to have missed the sarcasm so removing the comment
1 hr
|
I did understand the sarcasm and my reply was also only half-serious. Anyway, thanks!
|
4 KudoZ points awarded for this answer.
Comment: "Thanks a lot for the fine-grained explanation of the difference."
+1
5 hrs
Please see explanation
o.d.
stands for: omni die
meaning: every day (once daily)
comment: (preferred to "qd" in the UK[9])
q.d./q.1.d.
stands for: quaque die
meaning: every day
comment: mistaken for "QOD" or "qds," spell out "every day" or "daily". AMA style avoids use of this abbreviation (spell out "every day")
https://en.wikipedia.org/wiki/List_of_abbreviations_used_in_...
--------------------------------------------------
Note added at 5 days (2022-08-05 21:26:04 GMT)
--------------------------------------------------
This source says o.d. stands for "omne in die":
OD or o.d., an abbreviation used in medical prescriptions for omne in die or "once daily" both meaning "take once every day"
https://en.wikipedia.org/wiki/OD
stands for: omni die
meaning: every day (once daily)
comment: (preferred to "qd" in the UK[9])
q.d./q.1.d.
stands for: quaque die
meaning: every day
comment: mistaken for "QOD" or "qds," spell out "every day" or "daily". AMA style avoids use of this abbreviation (spell out "every day")
https://en.wikipedia.org/wiki/List_of_abbreviations_used_in_...
--------------------------------------------------
Note added at 5 days (2022-08-05 21:26:04 GMT)
--------------------------------------------------
This source says o.d. stands for "omne in die":
OD or o.d., an abbreviation used in medical prescriptions for omne in die or "once daily" both meaning "take once every day"
https://en.wikipedia.org/wiki/OD
Peer comment(s):
agree |
Neil Ashby
7 hrs
|
Thank you!
|
|
neutral |
philgoddard
: But what's the difference, if any?
16 hrs
|
According to an internet Latin to English dictionary, the two mean the same thing (every day). I don't understand Latin. Perhaps a translator native in a Latin-related language can explain it better.
|
|
neutral |
Yvonne Gallagher
: I don't see any explanation here?
1 day 9 hrs
|
Discussion
We don't need a Latin expert but a medical one to tell us if these distinctions would be normal
just a guess
Amikacin 15 mg/kg *q.d* (every day) = the 15 mg/kg is the dose for one whole day, but may be possibly taken as 3 times 5 mg/kg each day / every 8 hours, not necessarliy as the whole 15 mg/kg once a day
once daily = the whole daily dose is taken in one go.